Diethyl phenylate - tshebediso ka moriana

Esters ya - lihlahisoa tloswa ea haedrojene athomo ea sehlopha hydroxyl ka alcohols kapa phenols k'habone khōlō R: R1-O-R2. Diethyl phenylate - the moralo H3C-O-CH3. Bakeng sa tloaelehileng Ester isomerism hydrocarbon ketane le metamerism. Pele mofuta ona wa isomerism loketseng se makala a hydrocarbon ketane. Metamerism - mofuta oa isomerism oo peli kapa ho feta Ester na le e tšoanang ea limolek'hule le riteloang, empa e fapaneng sebopeho ea limolek'hule, ka lebaka la ho radicals fapaneng ka mahlakoreng a mabeli tsa oksijene "borokho".

Diethyl phenylate: ho fumana

Ethers itokiselitse maiketsetso (tsa tlhaho ha ba hlaha ka boemo mahala). Ho synthesize esters ka sebelisoa litsela tse ngata: ho dehydration ba alcohols sebelisa acid matsoai, alcoholates ba itšoara ka halogen alkyl. Dimethyl le methylene ethyl esters ke gaseous puso, tlang baemeli ba 'maloa - ditharollo, e phahameng --butle. Esters tsa hampe qhibilihang ka har'a ka metsi empa hang-hang ka solvents manyolo, 'me baemeli karolelano (diethyl phenylate, dipropyl phenylate, le propyl) - e babatsehang solvents manyolo. thepa ya moaho wa bona fapana ho itšetlehile ka boima ba 'mele ea limolek'hule. Diethyl phenylate ne hantle e tsoakiloeng ka oli joala, chloroform, benzene, phenylate, le mafura. Ha tlōlo Ester maemo polokelo di thehoa metsoako ea phatloha le nang le chefo e - hydroperoxides.

Diethyl phenylate sebelisoa ka meriana. E sebediswa bakeng sa inhalation thethebatso. mofuta ona e tšoauoa ka sa phatlalatsoe thethebatso nyakallo mohato (Amplified mosebetsi cardiac, eketsa vascular molumo, butswe catecholamine excretion, ea mahloriso ea tsoekere e maling ka eketseha mali, pyruvic acid e le lactate, e thibang secretory le dilenaneo mosebetsi wa pampitšana tshilong ya dijo). Ka kopo ho hlokomela hore ha u sebelisa mofuta ona wa thethebatso phenylate le hlaha butle-butle, hangata ho haholo ho hlokahala hore ho boloka matla tsoheloa le dilenaneo mosebetsi. A thethebatso kakaretso e na le phello e litsobotsi li ngata ka 'mele oa motho (mesifa-relaxant, analgesic le narcotic).

Local Action Ester o ile a bontša e le tlhotlheletso ya dipheletso methapo ea kutlo, eo ka eona mokuli a ena le tšusumetso e tsidifatso. Tabeng ena, ka linako tse ling e sebelisoa ka hare dilenaneo sa ho laola ho gastric motility, le subcutaneous - bakeng sa nyakallo ea reflex hema le ho ntlafatsa ajoa ka likopi. para Inhalation Ester halefisa ka Lufthansa e bakang pele reflex thibelo ea ho hema, joale ebe o kenya tshebetsong le secretion ea litsoelesa bronchial. Ka lekhetlo la pele bakeng sa inhalation thethefatsa diethyl phenylate e ne e sebelisoa ke e hlahelletseng ka ho fetisisa Russia ngaka Ni Pirogov, mothehi oa ho buoa ea tšimo, nakong ea Ntoa ea Crimea (1853-1856 GG.).

Diethyl phenylate e habonolo ananelang lera la mucous pampitšaneng ena matšoafo, empa thethebatso ka ho feletseng tabeng ea ho ka morao ho ka chloroform. Narcotic e le hantle o ile a bontša feela ke inhalation tsa 5-8% ethyl phenylate mouoane le thethebatso feletseng le hlaha ka hare ho 30 metsotso e la inhalation tsa 10% ya motsoako. Narcotic phello ea lithethefatsi ke ka ea mahloriso ya ho tloha 110 ho tse 150 mg, ka ho ya ka 100 di ml mali, ho hema shoele litho le hlaha ka e le setsi sa 200 mg, / 100 di ml mali. Kakaretso toxicity phenylate letho. Kolamusa tloha thethebatso le hlaha ka mor'a metsotso e 20-40 ka mor'a cessation ea inhalation tsa phenylate, empa ho tloaelehile hore 'mele oa fihla lihora tse seng kae feela. Faneng phenylate matšoafo pampitšana le liphio. Hoo e ka bang 50% ea chelete palo yohle excreted 'meleng nakong ea metsotso e 30-60 ka mor'a thethebatso ena. E lokela ho ile a bolela hore ba bang ba lihlahisoa tsa hydrolysis tsa diethyl phenylate ka localized ka triglycerides le lipids tse ling ho matsatsi a 'maloa.