Thyroid li-hormone: mohloli, boleng ba bolwetse

'Mele oa motho - tsamaiso lehafing oo dithulaganyo tsohle li laoloa ke ba bang. Le leng le le leng 'mele oa ka sebopeho lona thusa hore ho ho boloka botšepehi ba mosebetsi.

Hammoho le boko bo ke o mong oa mechine ea bohlokoa ka ho fetisisa taolo - batho endocrine tsamaiso. Ho phethahatsa bohato lona ke litsoelesa endocrine, eo secrete-hormone le makgetha a ho itseng le tropism itseng bakeng sa lisele phofung. Kahoo, thyroid tsoelesa e phetha karolo ea bohlokoa ka ho ntshetsopeleng ea 'mele ea' me e ama tsohle mefuta ya phapanyetsano. O ile a bontša hore ho li-hormone thyroid, eo kenya letsoho hore ho 'meleng, ntshetsopele ba kelello ho bana ba, fana ka metabolism le matla a batho ba baholo. Ka lehlakoreng le leng, tlhahiso bona e laolwa ke tsamaiso ea methapo, dintho e leng bioactive pituitary le hypothalamic lokolla lintlha. Kahoo, thyroid li-hormone tse kamehla ka boemo ba itseng ka mali le eketsa mele oa ba nang le litlhoko tse khethehileng, mantle a bona ka boela bontša ho hloka thyroid mosebetsi le a iodine litareng e.

hormone

Glandula thyroidea (thyroid) o khomaretse trachea le na le letona 'me a setse lobes amana ke mochophoro oa. Ka ho toba tswakana hormone ea thyroid o etsoa ka follicles lona tlala colloid ka hare, e leng e thehiloe protheine - thyroglobulin. Ka iodination eketsehileng ba litlhaka kahare tyrosine ka sebopeho sa eona 'me e ileng ea latela sehlogo tsa metsoako fumana le thehoa triiodothyronine le tetraiodothyronine (T3 le T4). hormone tireiodnye Ho ekelletsa moo tswang thyroglobulin molek'hule khomaretse le lokolloa ka maling ka mahala foromo. Ba na le concentrations fapaneng, 'me li fapana ka potency (T3 e emela tekanyetso haholo ka tlaase, empa potency lona o moholo haholo ho feta hore ba T4). Leha ho le joalo, phello ea li-hormone 'mele ba na le e tšoanang: kgothaletsa mafura le k'habohaedreite metabolism (eketseha maemo tsoekere) thunye gluconeogenesis, sebete glycogen thibela metsoako sebopeho le ntlafatsa protheine tswakana (ka chelete ka tsela e feteletseng, lehlakoreng le leng, ntlafatsa disintegration ea bobeli).

Ho e bontšoa ke 'nete ea hore ba boloka khatello ea mali le ho otla ha pelo le mocheso oa' mele, potlakisa dithulaganyo kelellong le maikutlong. Ka nako embryonic thyroid li-hormone tse ikarabellang ho khethollo ea ba lisele ho pholletsa le 'mele. Bongoaneng, kenya letsoho hore ho ho hōla le ntshetsopele ba kelello ba ngoana. Ho phaella moo, ba ntlafatsa erythropoiesis, tlaase reabsorption tubular tsa metsi.

lefu

Ka ba bang ba mafu a, thyroid li-hormone secretion e fokotsehile (hypothyroidism). Tabeng ena, ba lokela ho nkeloa sebaka ke meriana. Hore ka buseletsa bakeng sa lebaka la ho hloka thepa ea motheo dikahare joalo BAKC thyroid li-hormone? Lithethefatsi sebelisoa tabeng ena - ke "Levothyroxine" (T4), "Liotironin" (T3) le mefuta e fapaneng ya lithethefatsi a iodine litareng e-nang le. Ka mosing, 'me feteletseng thyroid li-hormone lebisa mafu tshilong ya dijo ka' mele tse ea bongaka e bonahale tlōla homeostasis le psychomotor mosebetsi. Tekanyo ea tšenyo e itšetlehile ka lilemo tsa ho ba le mamello e (cretinism feela bana), boemo ba khaello kapa feteletseng hormone (hyperthyroidism 1, 2, 3 likhato). Qetellong ho na le bokhutšoanyane phefumoloho, palpitations, e ile ea eketseha khatello ea mali, lefu la ba mefuta eohle phapanyetsano. Ka ho hloka, ka fapana le hoo, fokotseha metabolism, mokuli e ba la noaboloha, tsotelle.