Sebedisana trimoxazole - likhothaletso Kopo

Sebedisana trimoxazole ke moemeli loantsang likokoana tse e fumaneha ka tharollo bakeng sa infusions, liente, matlapa, suspensions, bakeng sa-ja. Ka sehloohong metsoako mafolofolo ho lokisetsa itse ke sulfamethoxazole le trimethoprim, le ka tlaasana - tlaase limolek'hule boima polyvinylpyrrolidone, k'halsiamo stearate, le starch litapole.

ho bonahala

Sebedisana trimoxazole e sebelisoa ka ho ba teng ha mafu a tšoaetsanoang:

- serame sa matšoafo, empyema, a hlobaetsang le a sa foleng la bronchitis, matšoafo abscess, bronchiectasis ;

- epididymitis, prostatitis, urethritis;

- chancroid, qhoshola, granuloma inguinale, lymphogranuloma venereum;

- feberu ea mala, baktheria letšollo, paratyphoid e feberu, shigellosis, cholangitis, gastroenteritis, k'holera, feela e le karolo ea phekolo motswako;

- tšoaetso ea leqeba, maqoqomete, pyoderma, abrasions, dinama tse nyenyane tse bonolo abscesses, erysipelas;

- sinusitis, nattokinase phatlalatso, laryngitis;

- boko abscess, septicemia, a hlobaetsang le a sa foleng osteomyelitis, meningitis, a hlobaetsang le brucellosis, malaria, toxoplasmosis, Amerika Boroa blastomycosis, ea ho phekola ba khohlela whooping e mpa e le karolo ea kalafo e rarahaneng.

Sebedisana trimoxazole - litaelo tsa tšebeliso

meriana ena lokela ho ho nkoa ka ka makhetlo a mabeli letsatsi ka dikgao tsa lihora tse 12. Bakeng sa bana ba lilemo li dilemo tse 3 ho ea ho 5, e lethal dose ea se nang molekane ke 240 mg, ea lilemo li dilemo 6-12 - 480mg, 'me ka mor'a 12 - 960mg.

Ka tloaelo ho, ho phekoloa mafu a tsoaetsanang a hlobaetsang le ha matsatsi a tlase ho 5, empa ka mor'a ho nyamela ha matšoao a bonahalang ea lefu lena le ke ho hlokahala hore ho nka matlapa a bakeng sa matsatsi a mabeli ho feta. Kalafo ea mafu a kang lymphoma inguinal, la bronchitis foleng, a hlobaetsang le nattokinase phatlalatso, chancroid ka nka ho fihlela ho ka libeke tse peli 'me ho fihlela ho ka khoeli ea brucellosis hlobaetsang le feberu ea mala kapa paratyphoid e ho fihlela ho likhoeli tse 3.

Ea ho phekola ba bonolo qhoshola sebelisa lithethefatsi "Co-trimoxazole" taeo e bontšang hore lethal dose e lokela ho ba ho 480 mg, ka makhetlo a mabeli ka letsatsi, empa ka e nkang 2400 mg, mong le e mong lihora tse 8 ho hlokahala hore ho hape ho etsa ka tsela e lekanang, empa ee boetse ke khoneha le 'ngoe tshebediso ya lithethefatsi ka ka tjhelete e ya 3840, mg.

Bakeng sa ho phekoloa mafu a tsoaetsanang gonococcal Co-trimoxazole e nkiloeng makhetlo a mararo ka letsatsi le 960 mg, bakeng sa beke.

Phekolo ke malaria e ba khanna matsatsi a 2, lithethefatsi e nkiloeng habeli ka letsatsi ho bo-1920, mg.

setlamorao

Holim 'a fumana le bolela "Co-trimoxazole" a ka hlaha liketsahalo tse sa rateheng tse kang pancreatitis, dyspepsia, ho ipolaisa tlala, pseudomembranous enterocolitis, ho nyekoa ke pelo, stomatitis. Ho ka 'na boela la hlaha aplastic khaello ea mali, methaemoglobinaemia, agranulocytosis, eosinophilia, hypoprothrombinemia, crystalluria, interstitial nephritis le ho hloleha renal.

Ho amohela moriana ka etsa hore meningitis aseptic, hlooho e opang, arthralgia, hyperkalemia, lekhopho, ho hlohlona, feberu.

Haeba ho na le litla-morao, o lokela ho ba khaotse ho ho nka lithethefatsi. Haeba ho na le ke hlokahala hore ho e sebelisa ka nako e telele, ho ke ke ho hlokahala hore ho ho laola ho hlophisoa mali a pheriferale, le liphio le sebete. Ho thibela ketsahalo ea crystalluria, ka go tlhaolega ka nako ya letsatsi le ho noa a etsang dilitara bonyane 3 of mokelikeli.

Contraindications

E tieo hanetsoeng ho sebelisa moriana o ka ho ba teng ha agranulocytosis, khaello ea tsoekere-6-phosphate dehydrogenase, hypersensitivity ho metsoako e, B12-khaello khaello ea mali, sebete kapa a liphio hloleha, hyperbilirubinemia ka bana, leukopenia, ka molomo ho bana ba ka tlaase likhoeli 2 le parenterally ho bana ba ka tlaase lilemong tse 6.

Overdose "Co-trimoxazole"

Tabeng ea overdose, o ile a re ho bolela ka etsahala crystalluria, hlooho e opang, ho ipolaisa tlala, bofokoli, ho nyekoa ke pelo, bohloko ba ka mpeng, hematuria, 'me ho otsela ho. Maemong a joalo ho ke ke ho hlokahala hore ho phetha gastric lavage, mokelikeli e tshelwa e le hore ho lokisa electrolyte pherekano, hemodialysis khoneha.