"Dipyridamole": litaelo ho sebelisoa. "Dipyridamole": ulasan pelanggan le analogues

ke lithethefatsi "Dipyridamole" ke efe? Litaelo, theko, libōpeho, 'me ho bonahala ba chelete li tla hlahisa mona ka tlase. Re boetse re u bolella hore hoa khoneha ho fumana itse lithethefatsi nakong ea bokhachane, ha a ne a analogues efe kapa efe, litla-morao 'me contraindications.

Sebopeho, paka le sebopeho

Le bontšang hore ba lokisetsa ho ea bukana amohele taeo? "Dipyridamole" - lithethefatsi e nang le mofuta o itseng oa ho lokolloa. A re ke re tšohleng lipotso tseo ka ho qaqileng le ho feta:

• Dragee 0.075 le 0.025, ba mafolofolo ba boleng ba sebele ba foromo ena e dipyridamole. Lithethefatsi e rekiswa liphutheloana polasetiki ea likotoana 100.
• "Dipyridamole" - matlapa a 0,075, 0,005 le 0,025 g, a tlotsitsoeng, ba boetse ba na le ntho a sebetsang a kang dipyridamole. Mabapi le thepa ea motheo e thusang, e qetellang kenyeletsa k'halsiamo stearate, lactose monohydrate le starch. Meriana e rekiswa ho blister 120 kapa 40 likoto, tse kenngoa ka e le qubu ea lebokoso.
• A tharollo bakeng sa ente. foromo ena e akarelletsa e tšoanang lithethefatsi a sebetsang. 0.5% tharollo e rekiswa ho vials 2 di ml.

pharmacodynamics

ke thepa nkoa meriana efe? Hona e khomaretse ditaelo bakeng sa tshebediso ya? "Dipyridamole" - lithethefatsi o nang le vasodilating sebediswa. bohato joalo e na le haholo-holo ka lijana gogoga.

O ile a amohela litekanyetso li behoa ea moriana o thibela mamarello tsa liplatelete eketsa sekhahla phallo ea mali, ntlafatsa le fetolela bohato angioprotective. Ho feta moo, ho bolela thuto.bafuputsi ba khothalletsa peeletso ajoa ka lijana tsa pelo.

Re ke ke ra bolela hore lithethefatsi normalizes venous outflow. Ka lebaka leo, ho noa lona kamehla haholo ho fokotsa kotsi ya thrombosis, haholo-holo ka nako postoperative.

Molao-motheo oa ho sebetsa

lithethefatsi life tse ling tse nang le thepa ea "Dipyridamole"? e re Manual eo e bolela hantle lowers le molumo oa methapo ea bokong. Tabeng ena, e haholo ka mafolofolo sebediswa bakeng sa litlhaselo tsa e fetang ischemic. Ho feta moo, ho nkoa e le ea lithethefatsi ntlafatsa haholo placental ajoa. Tsobotsi ena lumella u ho thibela fetal hypoxia.

ke mochine oa ketso ea lithethefatsi ea Ke Eng? Ke boitsebiso bofe bo na le litaelo bakeng sa ho sebelisoa? "Dipyridamole" eketsa mosebetsi oa adenosine le ho fokotsa litleneng tsa lona lisele. O ile a re ntho e ama mesifa vascular ke thibela norepinephrine lokolloa, eo ha e le hantle, etsa hore e honyele bona, ho eketseha khatello ea mali le systemic vascular hanyetsa.

Hape re lokela ho hlokomela hore ka lebaka la ho thiba phosphodiesterase decreases ho lokolloa ha activators aggregation tsa li-platelet. Tsobotsi ena thibela bona, ho tloha ho khomarela. The fokotseha ka adhesiveness platelet thibela clots mali ka lijaneng tsa.

Lithethefatsi "Dipyridamole", theko ea eona e bontšitsoeng tlaase mona, e le mahlahana antiplatelet le atisa ho sebelisoa hammoho le asiti acetylsalicylic.

Pharmacokinetics

Ananelang nkoa le mokhoa oa ho ena le potlako. mahloriso lona lebetsoeng le e ile ea fihla ka metsotso e 60 ka mor'a tsamaiso.

Ho bokella ba ntho le mafolo-folo e etsoa myocardiocytes. Lithethefatsi undergoes metabolism ka sebete. Tabeng ea tlōlo oa 'mele ona tsa mosebetsi khoneha bokella.

ho bonahala

Moriana o "Dipyridamole" e balletsweng ke mafu a latelang:

• gogoga insufficiency foleng tlhaho;
• bakeng sa ho thibela occlusion tsa shunts le stents;
• angina;
• myocardial infarction (e seng feela ka mohato hlobaetsang);
• venous le ea bohlokoa thrombosis;
• ischemic leqeba;
• thibelo ea thromboembolism, haholo-holo ka mor'a tsereletsi buoa ka pelo;
• placental insufficiency;
• ho potoloha ha mali magazine;
• atherosclerosis ea maoto ea;
• mafu a microcirculatory se hlahang ho yona efe kapa efe;
• glomerulonephritis;
• DIC ka sepsis ka ngoana le toxicosis.

Contraindications

Ho ea ka litaelo tsa chelete e ke ke ea sebelisoa haeba bopengwi latelang:

• hypotension ;
• tsitsang angina;
• hlobaetsang myocardial infarction;
• hypersensitivity;
• arrhythmias haholo;
• decompensated pelo hloleha;
• sebete hloleha;
• hemorrhagic diathesis;
• mala liso, haholo-holo ba nang le tšekamelo ea ho tsoa mali.

O lokela hape re lithethefatsi ena e hlophisitsweng ba hlokolosi ho bana ba ka tlaase le lilemo li 12 'me a diabolololo. Ho feta moo, ho ke ke ha khoneha ho sebelisa moemeli entoe nakong putlama.

Litaelo tsa tšebeliso

"Dipyridamole" --ba khahlanong le thrombotic lithethefatsi tseo tlameha ho tsamaisoa feela ke ngaka ho ba teng.

Ka kakaretso, matlapa a le lipilisi nkiloeng ka molomo metsotso 60 pele lijo, khalase ea metsi. E le hore ba fokotsa e le hantle tena ka mucosa gastric lithethefatsi ka hlatsoa fatse le lebese mofuthu.

Litekanyetso li behoa 'me mokhoa oa tšebeliso ea lithethefatsi lokela ho hlomamisa feela ke ngaka ho itšetlehile ka lilemo tsa ho ba le mamello, ho bala le boemo ba hae ba bophelo.

Bakeng sa thibelo ea thrombosis laolwa 75 mg, ea moriana o 6 ka letsatsi (palo e kahodimodimo ea letsatsi le letsatsi lethal dose - 300-450 mg,).

Ha gogoga insufficiency sebelisa 25-50 mg, ea lithethefatsi ka makhetlo a mararo ka letsatsi. The lethal dose lebetsoeng le mmuso ena - ka 150-200 mg,.

E le hore ho thibela ho hoama ya stent palaeform le mamello o fuoa 50 mg, ea lithethefatsi (ka makhetlo a mane ka letsatsi) hammoho le asiti acetylsalicylic. The moriana o e sebediswa pele ke buuoe, hammoho le bekeng e ka mor'a.

Ha occlusive mafu vascular ea maoto le matsoho e ka tlaase e kgothaletswa ho nka 75 mg, ea lithethefatsi ka makhetlo a mararo ka letsatsi.

The litekanyetso li behoa ea letsatsi le letsatsi ea lithethefatsi ho bana ba itšetlehile ka boima ba 'mele ea bona (5-10 mg, ka ho ya ka lik'hilograma).

Ho ea ka litaelo tseo, nakong ea kalafo e hlokahalang ho fokotsa tshebediso ya tee le kofi, ha ba ntse ba ka fokolisa phello ea meriana.

overdose

Ha u sebelisa tekanyetso e phahameng ea lithethefatsi matšoao a latelang a ka hlaha ka mamello: tlaase khatello ea mali, ho tsekela, e ile ea eketseha ho otla ha pelo le mali. Tabeng ena, emisa ho ea lithethefatsi le batla keletso ho ngaka.

liphetoho tse bohloko

Ho latela likarabo tsa bakuli, maemong a mang, tsa mokete oa chelete ho ka etsa hore liphello tse latelang lehlakoreng:

• kulisa;
• palpitations pelo;
• theola khatello ea mali (haholo-holo ha tsamaisoa entoe);
• thrombocytopenia;
• hlooho;
• mafu a dyspeptic;
• lerata hlooho;
• e phallang ea sefahleho;
• tachycardia;
• eketseha mali kapa tsoa mali.

ditshebeditsano lithethefatsi

e le hantle Antiplatelet ea moriana e ntlafatsoa ke tsamaiso tsoa hong le asiti acetylsalicylic, tetracycline, penicillin, cephalosporin, anticoagulants sa tobang le asiti nicotinic.

Ho lokela ho hlokomeloe hore ho anticoagulants sa tobang, thrombolytics le heparin ka eketsa monyetla oa mathata a tsoa mali.

Re ke ke ra bolela hore caffeine le xanthine lithethefatsi fokotsa vasodilating le litla-ba khahlanong le thrombotic tsa chelete, 'me antacids fokotsa absorption lona le ho fokotsa ho tsepamisa mohopolo le maling.

Mabapi le ho ba lokisetsa ho a hlalosa, ho eketsa liphello tsa lithethefatsi antihypertensive.

Nka sebelisa meriana "Dipyridamole" nakong ea bokhachane?

Litsebi li bolela hore ha nka ka eona chelete ka bakhachane hlahisa mathata. Ho fapana le moo, lithethefatsi "Dipyridamole" nakong ea bokhachane e atisa ho laetsoeng ha ho na le kotsi ea senyeheloa ea ngoana kapa placental insufficiency.

Litheko le analogues

Lithethefatsi ka nkeloa sebaka "Dipyridamole"? Analogs tsa chelete tse thathamisitsoeng mona ka tlase. Tsena li akarelletsa lithethefatsi tse latelang: "Parsedil", "Kurantil", "Padikor", "Antistenokardin", "Trankokord", "angina", "persantin", "Dipyridamole-Verein". Kaofela ha lithethefatsi tsena li ka ba le e tšoanang le mafolo-folo motsoako. Leha ho le joalo, ba ka 'na ba le liphello tse fapaneng lehlakoreng le contraindications. Tabeng ena, e kgothaletswa ho sebelisa chelete tsena feela ka mor'a hore rerisane ngaka ya hao.

Ke bokae sethethefatsi "Dipyridamole"? theko lona ranges ho tloha 380-420 li-ruble (ho itšetlehile ka ka tjhelete e le mofuta o mong oa ho lokolloa lithethefatsi).

Reviews

Hangata ka ho fetisisa, ditshwaelo tsa hao mabapi le thulusi ena e setseng ka tseo bakuli bao ho bona ho ile ba laela hore ho thibela le kalafo ea pele ho nako placental botsofali, hammoho le placental insufficiency.

Re lokela ho hlokomela hore basali ba baimana le bothata ba jwalo lithethefatsi e ntle e molemo. 'maloa ba bong bo hlokang leeme feela le itšoare ka e bohloko ka mokgwa wa le ho fokotseha ha khatello ea mali le ho tsekela.