Sulfasalazine. Litaelo tsa tšebeliso

Moriana o bitsoang "Sulfasalazin EN" ke lefu le khahlanong le ho ruruha, ho loantšana ha maikutlo, lefu la immunosuppressive, bacteriostatic intestinal. Mechine ea ho ipapisa le lithethefatsi e itšetlehile ka thepa ea likarolo tse sebetsang.

Ntho e sebetsang ea salazosulfapyridine ke lithibela-mafu tse tsoang sehlopheng sa sulfonamide. Karolo e na le liketsahalo tsa bacteriostatic mabapi le gonococcus, streptococcus, diplococcus, E. coli.

Karolo e sebetsang ea 5-aminosalicylic acid e na le thepa e khahlanong le ho ruruha, e khothalletsa thibelo ea prostaglandin synthesis le ho tlosoa ha cyclooxygenase.

"Sulfasalazine" (taelo ea tšebeliso e na le boitsebiso bo joalo) e sitisa phetoho lymphocytes le ho thibela monocytes. Moriana ona o ama tšoaetso ea meriana ea cellular le ea boitšoaro bo hlephileng.

Meriana ha e sebetsane hantle le tšebetso ea lijo.

Tlhahiso ea lithethefatsi "Sulfasalazin" bakeng sa tšebeliso e khothalletsa hore ulcerative proctitis e se ke ea hlola e e-ba le lefu la ho bolaoa ke ulcerative. Meleng ena, meriana e sebelisoa kalafo ea ho fokotsa matla le e le phekolo ea tlhokomelo molemong oa ho fokotsa.

"Sulfasalazine" e kgothaletswa hore e sebelisoe ke lefu la Crohn's (e nang le mefuta e itekanetseng le e bonolo nakong ea boemo bo matlafatsang).

Lithethefatsi le tsona li laeloa bakeng sa ramatiki ea lefu la masapo (bana ba akarelletsang).

Meriana "Sulfasalazine" litaelo tsa tšebeliso e khothalletsa ho nka lijo ka mor'a lijo. Litekanyo li lokela ho behoa ka bomong ho ea ka matla a matšoao, hammoho le litla-morao tse ka khonehang.

Hangata, batho ba baholo ba laeloa ho tloha ho 500 ho ea ho 2000 milligrams ka makhetlo a mane ka letsatsi ho tsamaisa ponahalo ea mafu. Ka mor'a moo, mokuli o fetisetsoa tlhokomelo e tšehetsang. Tekanyo ka nako e le nngwe - limiligrama tse 500 ka makhetlo a mararo ho isa ho a mane ka letsatsi. Nako ea phekolo ke likhoeli tse 'maloa.

Tekanyo bakeng sa bana: ho tloha ho tse hlano ho isa ho tse supileng - milligrams 250-500 ho tloha ho tse tharo ho isa ho tse tšeletseng ka letsatsi, ho tloha ho tse supileng ho isa ho 0.5 dikgerama ka makhetlo a mararo ho isa ho a tšeletseng ka letsatsi.

Bakeng sa batho ba baholo, litekanyetso tsa bongaka ke 1.5-3 dikgerama. Joalokaha mokhoa o bontša, phello e tla ka mor'a libeke tse tšeletseng kapa tse leshome. Phekolo e tsoela pele ka bonyane likhoeli tse tšeletseng.

Meriana ena e hanyetsanoa ka lefu la phokolo ea mali, porphyria, mathata a tebileng sebeteng kapa liphio, hypersensitivity (ho akarelletsa salicylates, sulfonamides). U se ke ua laela lithethefatsi "Sulfasalazine" ho bana ba ka tlaase ho lilemo tse hlano. Ho hanyetsana ke nako ea lactation. Haeba ho hlokahala hore u sebelise meriana ha u anyesa, potso ea ho emisa lactation e lokela ho rarolloa .

Nakong ea bokhachane, lithethefatsi li ka fanoa ka mokhoa o tiileng ho latela litekanyetso tse fokolang tsa meriana tlas'a tlhokomelo ea bongaka. Ha ho kgothaletswe hore o noe moriana ona "Sulfasalazine" nakong ea boraro ea boraro ea bokhachane.

Boholo ba litla-morao tsa moriana o itšetlehile ka litekanyo tse nkiloeng 'me ke phello ea mosebetsi oa salazosulfapyridine (ntho e sebetsang).

Meriana e ka qholotsa nephropathy ea pherekano, ho ba le botenya, ho ba le methapo ea li-nephritis, ho ba le bothata ba ho robala, matšoao. Nakong ea phekolo, ho ka 'na ha e-ba le tlhaho e sa tloaelehang litšebeletsong tsa liphio, letšollo, thrombocytopenia, lisele tsa pulmonary, leukopenia, ho hloka matla le oligospermia (nako e khutšoanyane). Ho itšoara hampe ho boetse ho kenyelletsa ho hlatsa, ho tepella ha maikutlo, agranulocytosis, ts'oaetso ea anaphylactic, phokolo ea mali, urticaria. Maemong a sa tloaelehang, ho ka 'na ha e-ba le bothata mesebetsing ea tsamaiso ea methapo ea methapo, liketso tsa letlalo.

Nakong ea tšebeliso ea lithethefatsi ho kgothaletswa hore o sebelise bongata ba metsi.

Ha ho na bopaki ba hore meriana "Sulfasalazine" e na le lipapiso tsa motsoako o sebetsang.

Pele o sebelisa meriana, litsebi li khothalletsa ho bala tlhaloso.