Manaka tsa Plavix.

E mong oa antiplatelet phekolo kopantswe ke lithethefatsi, "Plavix". Kajeno e le tsona hangata haholo sebelisoa ka meriana, tse kang e manaka tsa Plavix zilt. Ea ho hlophisoa lithethefatsi akarelletsa clopidogrel le asiti acetylsalicylic. Ketso e khōlō ea ho lokisetsa le meriana e lebisitsoe ho thibelo ya ADP-receptor le boikarabelo ba ho aggregation ea lisele tsa mali (ka-platelet khetheha). A tsobotsi khethollang ya ba lokisetsa ho ea e etsolloa tlamme tsa ADP-receptors, leng isang le phello e tsitsitseng ka aggregation. Ka lebaka la mosebetsi receptor e tsosolositsoeng feela ka lefu la khale le tswakana tsa li-platelet le lecha. Joalo ke sebopeho le mochine oa ketso ea manaka tsa Plavix - zilta.

Clopidogrel (Plavix manaka) le sebelisoa ka litekanyetso li behoa ea ea 75 milligrams. Ka letsatsi la pele la ho nka lithethefatsi o ile a bontša ka attenuation bohlokoa tsa mosebetsi platelet aggregation. Holim 'a kopo morago ga moo e ba le phello e lithethefatsi eketseha. Hora ho lokisetsa Cycle meriana ke karolelano ea matsatsi a mararo ho a supileng. Mora discontinuation la phello ea lithethefatsi e hlokomela (ka botlalo ntlafalitsoeng ho fihlela ho fetisisa tsa platelet sebopeho) bakeng sa nako e 'ngoe ea matsatsi a mahlano ho tse supileng.

asiti Salicylic etsa hore thibelo ea platelet aggregation ka lebaka la ho etsolloa thibelo ea cyclooxygenase (Cox-1). Ka lebaka leo, fokotswa thromboxane tswakana le attenuated vasoconstriction. Joalokaha ke le nehile tsa clopidogrel hlohlelletsoa le phello e ba lula ba fetang bophelo ba lisele tsa mali (liplatelete).

Hobaneng sebelisa manaka tsa Plavix le lithethefatsi ka boyona? Tshebediso o tloaelehileng haholo oa motswako antiplatelet phekolo e loketse kotsing e khōlō ea vascular thrombosis ea sebakeng leha e le sefe ho ba teng ha diso atherosclerotic.

Ho na le ke e 'ngoe ho feta ratoa manaka tsa Plavix - listab. Leha ho le joalo, o ile a, joaloka tse ling tse ngata (klopilet, lopirel, plargil, detromb, plogrel, Trocken, kardutol), e sa ho pharaletseng sebelisoa ka ikwetlisetse morao-rao tsa bongaka.

Plavix kapa zilt?

lingaka tse ngata ho itšetleha ikutloeleng tshebediso ya Plavix, kaha katleho lona e se e bile ke liteko ea lotho. Bopaki bo botlaaseng moriana o ile ka khutlela ka 2007 'me ka lebaka la ho lilemo tse hlano tse fetileng, ho sebelisa mafolofolo feela matlafatsa e le sehlooho sa "molemo ka ho fetisisa sehlahiswa". Ha e le zilta, bokgoni lona, joalokaha ho boletsoe ka ho lingaka li bona, a batla a ka tlaase ho feta o ile a re, kahoo bapisoa le mphato oa lona mabapi le boleng ba phekolo ea meriana a ka se khonang ha ho joalo. Haholo-holo, bo-rasaense ba lumela hore bokgoni tlaase ea bobeli ke ka lebaka la ho se phethahale ha tsamaiso e theknoloji ea ho etsa thepa ea lithethefatsi. Biophysics tšoanang ela hloko tse ding kganetsano ka sebopeho limolek'hule pakeng Plavix le manaka a eona.

Ha e le theko, e haholo lahleheloang Plavix ziltu. Kahoo, theko ea pele ka makhetlo a mararo boleng ba bobeli. Maemong a mangata, litsenyehelo tsa ho ba ea lithethefatsi le isang ho hlokahala hore a sebelise counterparts sebetse hantle. Ka tiisetsa lingaka tsa litleliniking morao-rao, haeba u ke ke ea reka ea Plavix theko e phahameng ba lokela ho se reka theko e tlaase manaka lona - zilt. Ka ho feletseng lahla tumello ya moriana e sa kgothaletswa.

Ka lithethefatsi tse kang "Ko Plavix," ka nako eo ho eona ke pontšo ea ho litekanyetso li behoa ea eketseha ea karolo ea metsoako (100 le 75 mg, ea acid e salicylic, le clopidogrel, ka ho latellana).

Ka bomalimabe, ho fihlela joale difeme thekenoloji "Plavix" moriana o, hammoho le dikarolo tsa lona constituent tse theko e phahameng haholo, e leng e etsa hore theko e phahameng ea meriana. Molemong ho thusa bakuli ba ruileng tla analogues le molemo haholo ba lithethefatsi cha-lebitso.