"Doxazosin" moriana. Litaelo bakeng sa ho sebelisoa le tlhaloso

The moriana o "Doxazosin", theko ea tsona e ho tswa ho li-ruble 80 e na le hypotensive, mosebetsi vasodilating, o na le spasmolytic, hypolipidemic sebediswa. Ka ho fokotsa mesifa molumo oa lijana, lowers khatello ea mali le palo yohle pheriferale vascular hanyetsa. Tlas'a tšusumetso ea moriana o ka tšoauoa fokotseha HDL, palo yohle k'holeseterole, triglycerides, thibelo ea platelet aggregation le eketsa concentrations dinama tse nyenyane tse ea plasminogen mafolofolo. Le bolela "Deksazozin" (taeo e pukwanana tiisa tlhahisoleseding ya data) thusa ho fokotsa khatello le ho hanyetsa ka urethra e, ka sphincter hare. Ka mor'a ho amohela lithethefatsi e ananelang hantle haholo. The absorption ea moriana - 80-90%. Ha ho fumana absorption lijo e khoehlisa bakeng sa hora. Ea mahloriso lebetsoeng le e fihlellwa ka mor'a lihora tse tharo, ka nako ya baeti ba fihlelang ho mantsiboea - ka mor'a lihora tse hlano. Bioavailability - 60-70%. Metabolism le hlaha ka potlako ka ho lekaneng ho lisele sebete. Di behilwe moriana o foromo unmodified ka moroto ka metabolites, 'me ka intestine le.

Lithethefatsi "Doxazosin". Litaelo ho sebelisoa. ho khethoa ha

moriana buelloa ka kgatelelo ya madi e le adjunct e kapa ka monotherapy ka. E le karolo ea kalafo a ikopantseng a meriana abeloa le beta-blockers, diuretics thiazide, inhibitors Ace le ba bang. Ke matšoao a kenyeletsa nang kotsi ea tšoelesa ea senya hyperplasia mofuta (khahlanong le semelo sa khatello ea ho tloaelehile kapa e phahameng ea mali).

Contraindications

Medicine "Doxazosin" (taeo e pukwanana lemosa ka eona) ha ba abeloa tlaase ho lilemo tse lilemo tse leshome le metso e robeli, nakong ea diabolololo, tabeng ea hypersensitivity ka nako prenatal.

liphetoho tse bohloko

Nakong ea phekolo (haholo-holo ka mekhahlelo ea pele ea ho) ka 'na ba orthostatic hypotension, ea etellang pele ka hore maemong a mang ho fainting. Bakeng sa ho thibela boemo ena e kgothaletswa ho qoba ho fetola bohale boemong mele. Lithethefatsi "Doxazosin" (litaelo bakeng sa ho sebelisoa e bua ka eona) li ka baka ho tsekela, molomo o omileng, rhinitis, hlooho e opang, arrhythmia. Ka lebaka la ea moketeng oa lijo ho na le tachycardia, somnolence, arthralgia, bohloko sefuba, mafu cerebrovascular. litla bohloko tsa phekolo li akarelletsa mokhathala, kulisoa, angina, ho nyekoa ke pelo, rashes letlalo, incontinence mosese, mali nasal, pelo ea tlhaselo.

dosing Melao

The moriana o "Doxazosin" litaelo bakeng sa ho sebelisoa kgatelelo ya madi kgothaletswa ho qala ho nka 1 mg, hang (pele a il'o robala). Ka mor'a moo, ka tjhelete e ya lithethefatsi e eketsehile ho 16 mg, / ka letsatsi a. e lokela ho ba maemong a supine mor'a a e-ja ke bonyane tse tšeletseng ho lihora tse robeli bakeng sa ho thibela le lefu la "lethal dose ea pele". Le lekaneng Ntlafatso phello ea dosing e etsoa mor'a libeke tse 1-2 ho 2 mg,. Ka dikgao tsa matsatsi a supileng ho metso e mene chelete ea lithethefatsi e ile ea eketseha ka 2 mg,. prostatic hyperplasia kalafo o etsoang tsoa ka lethal dose ea la mg, 2 ho 4 ka letsatsi. The lethal dose palo e kahodimodimo - milligrams robeli ka letsatsi.