Benzylpenicillin sodium letsoai: litaelo ho sebelisoa. melao kopo

A sehloohong sena a re tla bua ka ho lokisetsa tse kang "Benzylpenicillin sodium letsoai". Litaelo bakeng sa ho sebelisoa, ho bonahala, litekanyetso li behoa 'me le dikgothaletso bakeng sa tšebeliso e tla koaheloa ka sehlooho se reng. Ho phaella moo, re nahana ka thepa diokobatsi la moriana, litla khoneha lehlakoreng le ditshebeditsano lithethefatsi le meriana e meng.

dipalogotlhe

Lithethefatsi ke moemeli loantsang likokoana le lithibela-mafu ho ba setho sa sehlopha se penicillin. Benzylpenicillin sodium letsoai ka boeona, litaelo bakeng sa tšebeliso ea eona e tla tšohloa mona ka tlase e hlahisoang ke li-fungus tse sa tšoaneng.

Lithethefatsi sehlopheng sena e sebediswa bakeng sa tsamaiso intramuscular, litla ka lisele tse sa tšoaneng le litho tsa ka hare ho eona le mali lopolla e nyenyane ea penicillin. Ho ea lithethefatsi o ile a qala ho ba le liphello tse ka boko le lesapong la mokokotlo 'me meninges, subarachnoid tsamaisoa.

Benzylpenicillin sodium letsoai, litaelo tsa tšebeliso: pharmacologically bohato

Lithethefatsi ke atlehang ka ho khahlanong le libaktheria a mob mobile ea HIV, e leng kenyeletsa:

• staphylococci;
• streptococci;
• pneumococci;
• metso o mosoeu ;
• coli koatsi;
• aerobiki (pholoha ka ho ba sieo ha oksijene) sporulating melamu.

Ho feta moo, lithethefatsi sebetsang khahlanong le a mob mobile mpe cocci (meningitis, gonococcus), spirochetes, actinomycetes le microorganisms tse ling. Penicillin e ile ea sodium letsoai ke thuso khahlanong le likokoana-hloko, rickettsiae, li-fungus, protozoa.

Lithethefatsi manganga mefuta e sa staphylococci, tse khonang ho hlahisa potlakisang tsebetso ea lik'hemik'hale penicillinase, disintegrating benzylpenicillin. The moriana o hlahisa mosebetsi tlaase ka ho phekola Pseudomonas aeruginosa, libaktheria mala le microorganisms tse ling, tse khonang ho abelwang karolo ya tjhelete e fapaneng ya penicillinase.

Pharmacokinetics

Ka lithethefatsi intramuscular ka potlako o kena maling, ho tloha moo e tlisoa maro a 'mele le lisele. Mabapi le ho mokelikeli cerebrospinal, ho kenella ka hare ho ea ho e nyenyane ea penicillin. Ea mahloriso phahameng ka ho fetisisa ea mali ka mor'a tsamaiso lona intramuscularly hlokomela mora mets 30-50. Ha ea lithethefatsi e ne e tsamaisoa subcutaneously, tekanyo ea absorption e fokotsehile 'me palo palo e kahodimodimo ea dintho maling tla hlokomela ka hora.

lihora tse tharo ka mor'a hore ente (subcutaneous kapa intramuscular) ya benzylpenicillin mesaletsa feela lula maling. Ka lebaka leo, ho ba le mahloriso tse phahameng tsa lithethefatsi 'meleng bakeng sa ho nako e telele, ho ke ke ho hlokahala hore ho a nkente ka ka mong le e mong lihora tse' nè.

Ha laolwa entoe, mahloriso tsa lona tsa moriana ka potlako oa oa. 'Me le hoja ho nka ka molomo benzylpenicillin e timetsoa ke penicillinase (potlakisang tsebetso ea lik'hemik'hale) le lero gastric.

Excreted lithethefatsi excreted ka moroto wa.

ya litatoli na

Ba lokela ho ka hloko a ithuta pele ho kgethwa ha moriana ka penicillin ho ile sodium letsoai, litaelo tsa tšebeliso, litekanyetso li behoa 'me ho bonahala ho sebelisoa. A re ke re qala ka ea bobeli. Kahoo, moriana e hlophisitsweng:

• ka mafu a matšoafo le pampitšana matšoafo;
• haholo mafu maswe;
• baktheria endocarditis;
• sepsis;
• tsoaetsanang le maqeba a nang le tšoaetso ea lisele tse bonolo, letlalo le lera la mucous;
• chesa;
• ho ruruha ea thapo lesapo la mokokotlo 'me boko, mazgovyh matlalo;
• purulent pleurisy;
• peritonitis;
• cystitis;
• Pius le septicemia;
• osteomyelitis;
• metso o mosoeu;
• sekareleta feberu;
• qhoshola;
• erysipelas;
• Tsoaetsanang ka masea;
• koatsi;
• mokaola;
• actinomycosis;
• inflammations tse fapa-fapaneng gynecological;
• mafu a hlabang ea 'metso, litsebe le nko.

Terms of Use le litekanyetso li behoa

Ho itšetlehile ka mefuta eohle ea phekolo tepelletse maikutlong sebelisa benzylpenicillin sodium letsoai ea lithethefatsi ka 'na ba ho tsamaisoa. Litaelo tsa tšebeliso, tsela ea tsamaiso le litekanyetso li behoa khoneha tla tšohloa ka ho re karolong ena.

Mokhoa oa ho kalafo lithethefatsi ka tšoarella, ho itšetlehile ka le lefu lena, ho tloha libeke tse 4 ho ea ho likhoeli tse 2 kapa le ho feta. moriana ka tsamaisoa ka litsela tse latelang:

• Intramuscularly ka quadrant ka holimo le ka ntle la gluteal ena. ho lokisetsa e hlapolotsoeng pele la taolo distilled metsi, novocaine kapa sodium chloride tharollo.
• Intravenous - .. feela tlas'a mafu joalo tse matla, tse kang meningitis, baktheria endocarditis, septicemia, joalo-joalo The lithethefatsi o laolwa mong le e mong hora 4 kapa e tsoelang pele rothele - 30 marotholi a ka motsotso ka lihora tse 6-12.
• Ho ka 'na boela ho tsamaisoa endolyumbalno benzylpenicillin letsoai sodium. Litaelo bakeng sa ho sebelisoa (ho sebelisa mokhoa) e fana ka mokhoa bakeng sa ho ruruha ea boko le lesapong la mokokotlo, ho akarelletsa le meninges ena. Lithethefatsi e tshelwa butle haholo - metsotso e 1-2.
• Ho na le Maemong a moo benzylpenicillin sebediswa bakeng sa injecting e hlabang foci. Ka mohlala, ha actinomycosis, letlalo leishmaniasis, pyoderma foleng le mafu a mang a tšoaetsanoang letlalo.
• Ka inhalations - bakeng sa kalafo le thibelo ea mafu a matšoafo le Lufthansa. Bakeng sa morero ona, tsoakane le tharollo benzylpenicillin sodium chloride kapa metsi distilled. Inhalations na ka makhetlo a fetang 2 ka letsatsi. Hlolang ka nako kalafo e mong - ho tloha metsotso e 10 ho e 30.
• E boetse e tshelwa ka mesothelioma kapa peritoneal cavity ka purulent peritonitis kapa pleurisy.
• Ka sebopeho sa hlatsoa, ditlotso, dressings mongobo, lotions le powders - bakeng sa chesa, maqeba a dinama tse nyenyane tse le bonolo, le osteomyelitis a al.
• Hape, tharollo ea lithethefatsi a sebelisa bakeng sa ho phekoloa mafu a ka holimo a matsoafo a le a ophthalmology.

Penicillin e ka sebelisoa ka phekolo hammoho le lithibela-mafu tse ling le litokisetso sulfanilamide. Moo le mokhoa oa ho tla matlafatsa phello phekolo ea lithethefatsi a sebelisa.

litla-morao

Ho ka boetse ha ba le tšusumetso e mpe ea benzylpenicillin sodium. Litaelo bakeng sa ho sebelisoa e bolela hore ba ile ba ba bontšitsoeng ke tsamaiso intravenous ya moriana hangata ka ho fetisisa.

Ha e le hantle, litla-morao tse amanang le kulisa ho moriana. Har'a matšoao a bohloko a re:

• candidiasis;
• hives;
• feberu;
• hlooho;
• chills;
• kopanetsoeng bohloko;
• Angioedema;
• eosinophilia;
• Mefuta e sa tšoaneng ea dermatitis;
• feberu;
• lymphadenopathy;
• anaphylactic makala - maemong a sa tloaelehang haholo.

Contraindications

Sa bakuli bohle ba ka atamela phekolo le moriana o ba letsoai benzylpenicillin sodium. Litaelo bakeng sa ho sebelisoa le melao ea tsamaiso fana maloa a contraindications. Har'a bona:

• mafu alejiki kang urticaria, feberu furu, bronchial asma, joalo-joalo.;
• hypersensitivity ho derivatives penicillin e;
• likarabo e sa tloaelehang ho lithethefatsi;
• lefu pathogen ho hanyetsa ka unit trust lethal dose ya benzylpenicillin.

Selelekeleng sa endolyumbarnym lithethefatsi ea nang le bokhoni o hanela ka ho lefu la sethoathoa.

Boimana le diabolololo

E behiloeng nakong ea bokhachane feela ha molemong ho kalafo ya basali o moholo ho kotsi le monyetla oa ho ngoana oa hae ea e-s'o hlahe. Ho seng joalo, lithethefatsi e sa tsamaisoa. kotsi karo-karolelano le bokgoni e laolwang ke ngaka ho ba teng.

Haeba ho hlokahala, le tsamaiso tsa tsa lithethefatsi nakong diabolololo lokela emisa kanyeso.

thepa

Lithethefatsi ntho benzylpenicillin letsoai sodium o na le mofuta o mong oa e tšoeu e metle bonaletsang phofo le tatso tse babang tseo hang-hang qhibilihang ka har'a e mokelikeli e.

moriana o habonolo timetsoa ke acid, alkalis, oxidizing mahlahana, potlakisang tsebetso ea lik'hemik'hale penicillinase, hammoho le futhumatsang. Lokisetsa lithethefatsi ntho e lokela ho ba hang-hang pele ho tsamaiso.

mehato precautionary

moriana o laolwa feela sepetlele ke lengolo la ngaka le ngaka le tlas'a tlhokomelo ea hae. Le temana ea phekolo lokela ho a hopola hore e lekaneng lethal dose benzylpenicillin kapa qetello ea pele ea kalafo ho ka etsa hore ho thehoe mefuta e itoanelang ea microorganisms. Ka ketsahalo ea ho hanyetsa kalafo ya ea lithethefatsi e tsoela pele lithibela-mafu tse ling.

Tšekamelo ea ho kulisa laolwa hammoho lithethefatsi antihistaminic ke benzylpenicillin sodium. Litaelo bakeng sa ho sebelisoa (ketso ea lithethefatsi e beuweng dintlha hae ho khetheha) tsebisa hore ha mokuli alejiki liponahatso phekolo hang-hang khaotsa.

Ka lihlopha tse itseng tsa bakuli (hōlileng, masea, fokolisitsoe ke ho kula) ka 'na na le ho hanyetsa benzylpenicillin, e bakang ntshetsopele ya superinfection.

Ka tšebeliso ka nako e telele, le sethibela-mafu ka ho hatella kapa karolo e 'ngoe timetsoa ke microflora mala, ea isang ho fokotswa tlhahiso ea divithamini tsa sehlopha B. Ka hona prophylactically bakuli, hangata e beuweng divithamini B1, B12 le ba bang.

Haeba, ka mor'a ho qala ha phekolo bakeng sa matsatsi a 3 e ne e sa bone phello e leha e le efe, ho ke ho hlokahala hore ho ea kalafo ho kopantswe kapa abela le lecha lithibela-mafu.

lemosa

Mehato abeloa batho ba nang le ho hloleha pelo le phytoteratology liphio mosebetsi benzylpenicillin letsoai sodium. Litaelo bakeng sa ho sebelisoa boetse e khothalletsa hore ho lebisa tlhokomelo e khethehileng ho fuoa tseo bakuli ba bolokile hypersensitivity ho cephalosporins.

Ka lebaka la monyetla oa ho fungal superinfection e kgothaletswa ho laela mahlahana a khahlanong le fungal.

Sebelisana le lithethefatsi tse ling

Ka ho kgethwa ha lithibela-mafu tsena, e nang le bacteriostatic, bohato bactericidal penicillin fokotsehile.

Ho lokisetsa "Probenecid" e na le thepa ea ka ea ho fokotsa secretion tubular ea lithibela-mafu e tlisoang ka ho eketseha ha boemo ba mali a ea bobeli 'me, e le lebaka leo, eketsa nako eo tlosa e le' mele.