Medicine "Tamoxifen" taeo ka kopo e amana le sehlopha se seng sa lithethefatsi antineoplastic le phello e nonsteroidal le antiestrogenic. Sebelisa moemeli ena di hlohleletsago ho lokolloa ha li-hormone pituitary, ho fokotsa ho ruruha le ka tsela e atlehang suspends ntshetsopele ya neoplasms. Ho qala ka la pele bozongisela ho na le masakana moriana ketso tsa estrogen bananeng, bakeng sa libeke tse 'maloa, ntle le etsa hore liphello tse sa rateheng-morao tse amanang le overgrowth ya dinama tse nyenyane tse. Bakuli motona ba nang le bothata ba ho ntsha peo, tšebeliso ea "Tamoxifen" le ka qholotsa ho eketseha ha concentrations lero la mali testosterone. Ha re hlahloba pharmacokinetics ba moemeli-ba khahlanong le hlahala, e qala ho ba le mafolo-folo ka mor'a metsotso e mashome a mararo feela ka mor'a hore tsamaiso ea, ho finyella tekanyo phahameng ka ho fetisisa ka mor'a lihora tse hlano ho isa ho tse supileng.
Fumaneha lithethefatsi "Tamoxifen" ka Letlapa foromo mosehla, e nang le e le motsoako o ka sehloohong milligrams leshome, mashome a mabeli, mashome a mararo kapa tse mashome a mane tamoxifen citrate. metsoako tse ding hape di: selulose, starch sodium, magnesium stearate, lactose le povidone. Khetla e na le ka sebopeho nhua polyethylene glycol lona, thaethaniamo dioxide e le hypromellose. Ho phaella moo, e nyenyane ea lactose teng moriana.
Abela lipilisi "Tamoxifen" taeo pukwanana khothalletsa hore bakuli ba endometrial kankere, tšoelesa ea senya kapa mae a bomme, le thoracic litsoelesa mammary. Hape, meriana ena ke e atlehang haholo bakeng sa lihlahala tse liphio kapa melanoma. Sarcoma e tšoanang ho qala ho nka lithethefatsi "tamoxifen". Litaelo bakeng sa ho sebelisoa tsa lintlha le liphello tse ntle ho tloha e sebelisa ea ho phekola ba etiologies tse fapa-fapaneng uzlovidnyh lihlopha.
Nka ena moemeli antitumor e tieo thibetsoe tabeng ea ho se mamellane motho ea tamoxifen citrate kapa metsoako leha e le efe ya moriana. Leukopenia, thrombophlebitis, bokhachane, diabolololo nako, lera le mefuta e mpe ea lefu la pelo le tsona contraindications ho lithethefatsi ena, "Tamoxifen" - litaelo bakeng sa ho sebelisoa ho ela hloko ho eona. Ho phaella moo, u se ke ua nka hore ho bakuli ba e amanang le sebete kapa renal insufficiency. Le tlhokomelo ea sohle se matleng a khethe pilisi "Tamoxifen" le thrombocytosis, thrombocytopenia, mafu a ea boko, kapa hypercalcemia.
lithethefatsi sena bang lihlopha tsa bakuli ba ka etsa hore indigestion, ho nyekoa ke pelo, ho hlatsa, cholestasis, fokotseha takatso ea lijo, letšollo, le khukhuneloa ha sebete. Pherekano, thrombocytopenia, hlooho e opang, leukopenia, ho otsela, feberu le molikoalikoane le ka boela la hlaha ka lebaka la ho nka lipilisi, "Tamoxifen". litla-morao kenyeletsa, 'me menyetla ea ho tsoa mali uterine, le tuka' me ho hlohlona ka makala genital, lihlahala cystic, urticaria, dermatitis le bronchospasm. Ntle le hore ho ka ba ho lemohiloeng fokotseha ka potency, lero ka bosaling, letlalo lekhopho le redness.