Lithethefatsi 'pronoran'. Litaelo tsa tšebeliso

(Lithethefatsi manaka tse kang "Tasmar," "selegiline" "Parkon" le ba bang) Medicine "pronoran" kenyelelitsoe dihlopha tsa mahlahana antiparkinsonian. The a sebetsang a motsoako o - piribedil. Lithethefatsi e fumaneha ka foromo Letlapa.

Ka mor'a ho kenella ka hare tsa motsoako o sebetsang ka potlako ananelang ho tloha tsamaiso tshilong ya dijo. Ea mahloriso palo e kahodimodimo ea lithethefatsi o ile a re ka mor'a hora e 'ngoe. Butle shoa hoa letlapeng "pronoran" e fana ka butle-butle lokolloa ha motsoako a sebetsang. mahloriso phekolo ea moriana nka lihora tse mashome a mabeli a metso e mene.

Ka e hlalosang mochine ea nkang khato ea ho ea lithethefatsi le "pronoran" taeo pukwanana bontša matla a ho ikitlaetsa vasodilating litla (eketsa ajoa mali ka lijaneng tsa mali ka maoto le matsoho e ka tlaase). Meriana di hlohleletsago dopaminergic tlhotlheletso le tšebetso ea motlakase ea cortex nakong robala le ha a ntse a falimehile, empa hape e ama mesebetsi e fapaneng, tse laoloang ke dopamine.

Medicine "pronoran" taeo pukwanana khothalletsa ka lefu Parkinson le mefuta monotherapy le tremor rarahaneng, kapa phekolo ho kopantswe (lefu mahareng kapa mathoasong a mefuta, tse tsamaeang le tremor). moriana o fuoa ka kalafo tse tlatsetsang bakeng sa ho hloka taolo bontshang matshwao ya mosebetsi dikopanothutano ya e le hantle a sa foleng 'me khaello sensorineural ka botsofali semelo sa (ho akarelletsa le litsebeng memoring ya le tlhokomelo). Ke matšoao a akarelletsa matšoao a mafu a mahlo a tlhaho ischemic (ho akarelletsa le ho fokotseha ha acuity bonwang, fokotswa fapana le hoo, narrowing tsa naha tse bonwang). E le phekolo adjunctive, litlhare "pronoran" taeo pukwanana khothalletsa hill claudication amanang le diso obliterative ka lipheletsong e ka tlaase.

A se ke a ho laela meriana ka ho putlama ea, hypersensitivity ho dikarolo, pelo ea matla le pathologies tse ling pelo le methapo. Lithethefatsi "litaelo pronoran 'bakeng sa tšebeliso e sa kgothaletswa ho nka hammoho le neuroleptics, ho ba le antipsychotic thepa matla (ntle le lithethefatsi" Clozapine ").

A ho ba sieo ya data ka tšeptjoang ka bohlokwa ba tsamaiso le polokeho ya moriana nakong ea bokhachane le ho diabolololo, basali ba baimana le lactating bolela se khethiloeng.

Baeti ba fihlelang ho "pronoran" lithethefatsi ka etsa hore flatulence, ho hlatsa, ho nyekoa ke pelo. le matšoao ana a felisitsoe, joalokaha ho le busa, ka mor'a phetoho e lethal dose. Maemong a mang, meriana le ka susumelletsa ho otsela, mafu a kelello (pherekano, restlessness). Ka tloaelo ho, matšoao a rarollwa mora discontinuation lithethefatsi. E ka seoelo ho keteka labile khatello ea mali kapa orthostatic hypotension, alejiki itšoara joang. Lithethefatsi "pronoran" (likarabo tsa bakuli le litsebi paka ena) isoa maemong a mangata hantle.

moriana e hlophisitsweng ka mor'a lijo ka hare. matlapa a ha ho hlokahale hore silakanya. moriana le metsitsoe kakaretso, ho noa metsi a lekaneng.

Ha kaofela ha ho bonahala ho (ntle le bakeng sa lefu le Parkinson), le lethal dose kgothaletswa ke Letlapa mong (50 mg,). Etellang lithethefatsi hang ka letsatsi. Haeba ho hlokahala (ka therisano le ngaka) o lumelloa ho eketsa litekanyetso li behoa ke halofo (mashome a mahlano milligrams habeli ka letsatsi).

Ka monotherapy bakeng sa lefu Parkinson kgetha 150-250 milligrams (matlapa a mararo ho tse hlano) ka letsatsi. Ka ho kopantswe phekolo meriana litekanyetso li behoa "pronoran" fokotswa ho milligrams 100-150 ka letsatsi (ho fihlela ho matlapa a mabeli kapa a mararo).

Ha Mokuli o kgatelelo ya madi ka nako le baeti ba fihlelang ho ya moriana o balletsweng ke kalafo antihypertensive.

Tshebediso ya lithethefatsi "pronoran" lokela ho laola setsebi.